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June 12-13


Day 1


7:30 a.m.      Registration; Continental Breakfast 

8:25 a.m.      Welcome: 2nd International Tremor Congress: 

                     From Bench to Bedside Towards Tremor Therapy Development  

                     Speaker: Sheng-Han Kuo, MD, Department of Neurology, Columbia University

Session 1: Tremor overview

Moderator: Sheng-Han Kuo, MD


8:30 a.m.       History of tremor research: from past to present.                               

                      Stanley Fahn, MD 


8:55 a.m.       Current understanding of tremor physiology                                      

                      Mark Hallett , MD


9:20 a.m.       Challenges in tremor research field                                                

                      Elan Louis, MD, MS


Session 2: Brain pathology of tremor

Moderator: Elan Louis, MD, MSc


9:45 a.m.       Molecular signatures for postmortem tremor brains: PD, ET, dystonia and  SCA                                               Phyllis Faust, MD, PhD 

10:10 a.m.    Cerebellar climbing fiber synaptic pathology in tremor                    

                     Sheng-Han Kuo, MD 

10:35 a.m.     Refreshment Break

Session 3: Animal models of tremor

Moderator: Vincenzo Gennarino, PhD


11:00 a.m.     Mouse models of essential tremor.                                            

                      Ming-Kai Pan, MD, PhD 


11:25 a.m.     Mouse models of ataxic and dystonic tremor                                      

                      Roy Sillitoe, PhD 


11:50 p.m.     Mouse models of dystonia, implication in tremor                              

                      William Dauer, MD


12:15 p.m.     Large animal models of tremor                                                    

                      Su-youne Chang, PhD


12:50 p.m.     Lunch

Session 4: Neuroimaging and Neurophysiology of tremor

Moderator: Sule Tinaz, MD PhD


2:00 p.m.      Stress modulation of tremor circuitry in Parkinsonian tremor      

                     Rick Helmich, MD, PhD

2:25 p.m.      TBD                            


2:50 p.m.      Distinct brain circuitry for essential tremor and dystonic tremor  

                     Aparna Wagle Shukla, MD                                                 


3:15 p.m.      Brain network changes in Parkinson’s disease and essential tremor   

                     Daniel Claassen, MD, MS 


3:40 p.m.      Refreshment Break

Session 5: Debate: ET plus- How should we deal with clinical heterogeneity of ET?

Moderator: Sheng-Han Kuo, MD

4:00 p.m.       Yes, we should use the term,ET plus                                          

                      Rodger Elble, MD, PhD 


4:20 p.m.       No, we should drop the term, ET plus                                            

                      Elan Louis, MD, MSc

4:40 p.m.       Discussion                                                                                        

                      Sheng-Han Kuo, MD

Session 6: Oral presentation 

Moderator: TBD

4:50 p.m.        Oral presentation of selected posters (Non-CME)


Session 7: Poster session (Non-CME)

Moderator: TBD

5:30 p.m.        Posters and Reception


7:30 p.m.        Adjourn

Day 2


7:50 am          Registration, Continental Breakfast


Session 8: Cerebellum and basal ganglia circuitry for tremor 

Moderator: Ming-Kai Pan, MD, PhD

8:30 a.m.        Purkinje cell synchrony for tremor generation                                            

                       Eric Lang, PhD


8:55 a.m.        Complex spike modulation for tremor                                                  

                       Wade Regehr, PhD

9:20 a.m.         Basal ganglia circuitry for tremor                                                                  

                        Un Kang, MD


9:55 am           Refreshment Break


Session 9: Clinical characteristics and video demonstration of diverse tremor disorders

Moderator: Christine Kim, MD

10:20 a.m.       Essential tremor                                                                 

                        Joohi Jimenez-Shahed, MD


10:40 a.m.       Tremor in Parkinson's disease                                                                      

                        David Charles, MD

11:00 a.m.       Ataxia and tremor                                                                      

                        Deborah Hall, MD, PhD

11:20 a.m.       Dystonia and tremor                                                                

                        Hyder Jinnah, MD, PhD

11:40 a.m.       Cognitive aspect of essential tremor                                    

                        Stephanie Cosentino, PhD

12:00 p.m.       Childhood tremor                                     

                        Bennett Lavenstein, MD

Session 10: Funding opportunities for tremor

Moderator: Serge Przedborski, MD, PhD


12:20 p.m.       NIH perspective                                    

                        Codrin Lungu MD and Daofen Chen, PhD

12:40 p.m.       International Essential Tremor Foundation                                    

                        Patrick McCartney

12:45 p.m.       National Ataxia Foundation                                    

                        Sue Hagen

12:50 p.m.       Parkinson’s Foundation                                    

                        James Beck, PhD

12:55 p.m. -1:35 p.m. Lunch (Parallel lunch for Young Investigators)

Session 11: Therapy development for tremor 

Moderator: TBD

1:35 p.m.         Pharmacological therapy development for tremor                                

                        William Ondo, MD

2:00 p.m.         Botulinum toxin for tremor                                                                

                        David Simpson, MD


2:25 p.m.         Advances of surgical and ablative therapies for tremor     


2:45 p.m.         Tolerance and circuitry re-organization of tremor                     

                        Alfonso Fasano, MD, PhD


3:15 p.m.         Break


Session 12: Current therapy development for tremor- Industry perspective (non-CME)

Moderator: Peter LeWitt, MD

3:35 p.m.         Pipeline development for selective industry partners                

                        Industry representatives

4:45 p.m.         Closing remark                                                                            

                        Ming-Kai Pan, MD, PhD


5:05 p.m.         Adjourn

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