April 30

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7:00am           Registration, Continental Breakfast 

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7:55am           Welcome: From bench to bedside towards tremor therapy development  

                 Sheng-Han Kuo and Aparna Wagle Shukla 

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Session 1:      Recent advances in Tremor Physiology and Clinical Science 

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8:00am          The Global Burden of Essential Tremor and the Economic Costs of Treatment     

                         Kandice Kapinos                        

 

8:20am          Prevalence and Clinical Significance of Common and Rare Tremor Disorders

                         Sanjay Pandey

 

8:40am          Postmortem-based Diagnostic Criteria for Essential Tremor

                         Phyllis Faust

 

9:00am         Neuropathological basis of ET-Dementia

                         Elan Louis

 

9:20am         Proteomic signatures of essential tremor

                         Giovanni Oliveros 

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9:40am         Distinguishing Parkinson's Disease Tremor from Essential Tremor: Clinical and                                             Experimental Tools             

        Matteo Bologna

 

10:00am        Neurophysiologic Signatures of Essential Tremor and Implications for DBS            

        Lauren Hammer

              

10:20am        Cerebellar EEG Signatures of Essential Tremor

                         Ami Kumar

              

10:30am        TBD (Selected platform presentation)

 

10:40am        Break

 

Session 2:      Basic and translational research of tremor: what do we learn?

                            

11:10am        Frequency Encoding Mechanism of Essential Tremor

                         Ming-Kai Pan

 

11:30am        Thalamic Gating of Movement Frequency: Implications in Tremor Disorders  

                         Christopher Chen

 

11:50am         Bi-directional Regulation of Cerebellar Physiology of Ataxia and Tremor

                          Sheng-Han Kuo

 

12:10am         Purkinje Cell Axonal Pathology of Essential Tremor

                          Hirofumi Fujita

 

12:30am         TBD (Selected platform presentation)

 

 

Lunch             1:00pm to 2pm (60 min)

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Session 3:       From Mechanisms to Medicine: Identifying the Key Pathophysiological basis underlying                              Essential Tremor and Parkinson’s disease for Targeted Therapies

 

2:00pm            Initial poll - What is the Main Mechanism for Essential Tremor?

                           Peter A. LeWitt

 

2:05pm            Hyper-excitability of the T type Calcium Channels is the Key Mechanism 

                           Theresa Zesiewicz

 

2:20pm             Insufficient GABA Mechanism is the Key Mechanism          

                            William Ondo

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2:35pm             Dopaminergic Dysfunction: A Central Contributor to Parkinsonian Tremor

                            Michiel F. Dirkx​

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2:50pm             Serotonin and not Dopamine: A Central Contributor to Parkinsonian Tremor

                            Jacopo Pasquini

 

3:05pm             Discussion 

                            Peter Lewitt

 

3:30pm             Refreshment Break 

 

 

Session 4:        Industry perspective (4pm-5:30pm) NON-CME

                           Moderator: Daniel Roque

 

5:30pm            Panel discussion- Academic and Industry Collaboration 

                           Moderator: Sheng-Han Kuo, Aparna Wagle Shukla and Daniel Alberto Roque 

 

6:30pm           Reception and Dinner: Sunset cruise at Tampa Bay (Registration Required)

 

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                                                                     May 1 

 

7:00am           Registration, Continental Breakfast

 

Session 5:      Recent Advances in Imaging of Tremor Disorders 

 

8:00am           Updates on Parkinson’s Disease Tremor Imaging

                         Rick Helmich

 

8:20am           New Insights of Dystonic Voice Tremor Imaging

                          Kristina Simonyan

 

8:40am            Enigma tremor

                          Max Laansma

9:00am            Mechanistic Insights Into Orthostatic Tremor

                          Marie Vidailhet

 

9:20am            TBD (Selected platform presentation)

               

9:30am            Refreshment Break 

 

Session 6:        Advances in Therapeutic Development for Tremor 

 

10:30am          Peripheral Neuromodulation for Tremor Management 

                           Rajesh Pahwa

 

10:50am          New Horizons in Tremor Management: Pharmacological Innovations and Clinical Trials

                           Peter Lewitt

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11:10am          Advances in DBS Therapy: Evolving Targets,  Adaptive Systems, and Precision                                               Neuromodulation

                          Aparna Wagle Shukla

 

11:30am         Thermal Lesioning with Precision: Updates on Focused Ultrasound Therapy for Tremor

                          Antonella Macerollo

 

11:50am         TBD (Selected platform presentation)

 

12:00pm        TBD (Selected platform presentation)

 

12:10pm        Lunch & Poster Sessions

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Session 7:      Parallel session 

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1:30pm          Electrophysiological Tools for Tremor Evaluation: What Every Clinician Should Know    

                         Katie Longardner

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 1:40pm          Decoding Head Tremor: Electrophysiological Tools for Diagnosis and Management.                                    Aasef Shaikh

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 1:50pm          Smart Wearables for Tremor Detection: Algorithms, Accuracy, and Clinical Relevance  

                          StevenCharles

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 2:00pm         Machine Learning Approaches to Understanding and Managing Tremor Disorders.  

                         Muthuraman Muthuraman​​

 

 2:10pm          Artificial Intelligence in Tremor Diagnosis and Management: Current Applications and                               Future Directions.

                           Nienke A Timmermans​

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​​​2:20pm           Work and Activity Impairment in Individuals with Essential Tremor.

                           Ludy Shih

 

Session 8:       Clinical and Research Mentoring

 

2:30pm           What Do We Need to Move Tremor Research Forward? Perspectives for the Next                                          Generation

                          Robert A. Hauser, Holly Shill , Daniel Roque and Abhishek Lenka

 

3:30pm           Refreshment Break 

 

Session 9:      Challenging cases & video rounds

 

4:00pm           Tremor Video Rounds: Case-Based Learning and Diagnostic Pearls

                           Steven Frucht and Hyder Jinnah

 

4:50pm           Closing remarks

                         Sheng-Han Kuo and Aparna Wagle Shukla