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SCHEDULE

Day 1            April 30th

                       

7:30 AM       Registration and Continental Breakfast

                       

8:25 AM       Welcome (5 min)

                        Sheng-Han Kuo & Aparna Wagle Shukla

                       

Session 1: Recent Advances in Tremor Physiology and Clinical Science

Moderator: TBD

                       

8:30 AM       The Global Burden of Essential Tremor and the Economic Costs of Treatment 

                        Kandice Kapinos                       

                       

8:50 AM       Prevalence and Clinical Significance of Common and Rare Tremor Disorders

                        Sanjay Pandey

                       

9:10 AM       Postmortem-based Diagnostic Criteria for Essential Tremor

                        Phyllis Faust

                       

9:30 AM       Neuropathological Basis of ET-Dementia

                        Elan Louis

                       

9:50 AM       Work and Activity Impairment in Individuals with Essential Tremor

                        Ludy Shih

                       

10:10 AM    Distinguishing Parkinson’s Disease Tremor from Essential Tremor: Clinical and Experimental  

                        Tools

                        Matteo Bologna

                       

10:30 AM    Cerebellar EEG Signatures of Essential Tremor

                        Ami Kumar (young investigator talk)

                       

10:40 AM    Proteomic Signatures of Essential Tremor

                        Giovanni Oliveros (young investigator talk)

                       

10:50 AM    Break (20 min)

                       

Session 2:   Basic and Translational Research of Tremors: What Do We Learn?

Moderator: TBD

                       

11:10 AM    Frequency Encoding Mechanism of Essential Tremor

                        Ming-Kai Pan

                       

11:30 AM    Thalamic Gating of Movement Frequency: Implications in Tremor Disorders

                        Christopher Chen

                       

11:50 AM    Neurophysiologic Signatures of Essential Tremor and Implications for DBS

                        Lauren Hammer

                       

12:10 PM     Bi-directional Regulation of Cerebellar Physiology of Ataxia and Tremor

                        Sheng-Han Kuo

                       

12:30 PM     Purkinje Cell Axonal Pathology of Essential Tremor

                        Hirofumi Fujita

                       

12:50 PM     TBD (young investigator talk)

                       

1:00 PM       TBD (young investigator talk)

                       

Lunch           1:10 PM to 2:00 PM

                       

Session 3:  From Mechanisms to Medicine: Identifying the Key Pathophysiological Basis Underlying Essential Tremor and Parkinson’s Disease for Targeted Therapies

Moderator: TBD

                       

2:00 PM       Initial Poll

                        Peter A. LeWitt

                       

2:05 PM       Hyper-excitability of the T-type Calcium Channels is the Key Mechanism for Essential Tremor 

                        Theresa Zesiewicz

                       

2:20 PM       Insufficient GABA Mechanism is the Key Mechanism for Essential Tremor

                        William Ondo

                       

2:35 PM       Dopaminergic Dysfunction: A Central Contributor to Parkinsonian Tremor

                        Michiel F. Dirkx

                       

2:50 PM       Serotonin and not Dopamine: A Central Contributor to Parkinsonian Tremor

                        Jacopo Pasquini

                       

3:05 PM       Discussion

                        Peter A. LeWitt

                       

3:30 PM       Refreshment Break (30 min)

                       

Session 4: Industry Perspective

Moderator: Daniel Roque

                       

4:00 PM       Industry Partner Presentations 

                       

5:30 PM       Panel Discussion - Academic and Industry Collaboration

                        Moderators: Sheng-Han Kuo & Aparna Wagle Shukla

                       

6:00 PM       Adjourn

                       

6:30 PM       Reception and Dinner: Sunset Cruise at Tampa Bay

                       

Day 2            May 1st

                       

7:00 AM       Registration; Continental Breakfast

                       

Session 5: Recent Advances in Imaging of Tremor Disorders

Moderator: TBD

                       

8:00 AM       New Insights of Dystonic Voice Tremor Imaging

                        Kristina Simonyan

                       

8:20 AM       Enigma Tremor

                        Max Laansma

                       

8:40 AM       Updates on Parkinson’s Disease Tremor Imaging

                        Rick Helmich

                       

9:00 AM       TBD (young investigator talk)

                       

9:10 AM       TBD (young investigator talk)

                       

9:20 AM       Refreshment Break (20 min)

                       

Session 6: Advances in Therapeutic Development for Tremor

Moderator: TBD

                       

9:40 AM       Peripheral Neuromodulation: Current Strategies and Future Directions in Tremor Management

                        Rajesh Pahwa

                       

10:00 AM    New Horizons in Tremor Management: Pharmacological Innovations and Clinical Trials

                        Peter A. LeWitt

                       

10:20 AM    Advances in DBS Therapy for Tremor: Evolvoing Target, Adaptive Systems, and 

                        Precision Neuromodulation

                        Aparna Wagle Shukla

​​

                       

10:40 AM    Thermal Lesioning with Precision: Updates on Focused Ultrasound Therapy for Tremor

                        Antonella Macerollo

                       

11:00 AM    Machine Learning Approaches for Understanding and Managing Tremor Disorders

                        Muthuraman Muthuraman

                       

11:20 AM    Artificial Intelligence in Tremor Diagnosis and Management: Current Applications and  

                        Future Directions

                        Nienke A Timmermans

                       

11:40 AM    TBD (young investigator talk)

                       

11:50 AM    TBD (young investigator talk)

                       

12:00 PM     Poster Session (90 min)

-1:30 PM

                       

12:30 PM     Lunch and Learn

                       

Session 7: Advances in Analysis of Tremor

Moderator: TBD

                       

1:30 PM       Electrophysiological Tools for Tremor Evaluation: What Every Clinician Should Know

                        Katie Longardner & Marcus Callister

                       

1:50 PM       Decoding Head Tremor: Electrophysiological Tools for Differential Diagnosis and Management

                        Aasef Shaikh

                       

2:10 PM       Smart Wearables for Tremor Detection: Algorithms, Accuracy, and Clinical Relevance

                        Steve Charles

                       

Session 8: Clinical and Research Mentoring (60 min)

Moderator: TBD

                       

2:30 PM       What Do We Need to Move Tremor Research Forward? Perspectives for the Next Generation

                        Robert A. Hauser, Holly Shill, Abhishek Lenka, Daniel Roque

                       

3:30 PM       Refreshment Break (20 min)

                       

Session 9: Challenging Cases & Video Rounds
Moderator: TBD

                       

3:50 PM       Tremor Video Rounds: Case-Based Learning and Diagnostic Pearls

                        Steve Frucht & Hyder Jinnah

                       

4:50 PM       Closing Remarks

                        Sheng-Han Kuo & Aparna Wagle Shukla

SPEAKERS

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Matteo Bologna MD, PhD
 

Associate Professor of Neurology

University of Rome La Sapienza
Rome, Italy

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Marcus Callister, MD

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Clinician Investigator, Instructor
NSI Neuro Behavioral MGPO, Mass General Research Institute

Massachusetts General Hospital

Boston, Massachusetts

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Steven Charles, MD, PhD

​

Neuroscience Center Director, Associate Professor, Mechanical Engineering

Brigham Young University 

Provo, Utah

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Christopher Chen, PhD

 

Assistant Professor, Neuroscience and Experimental Therapeutics

Penn State College of Medicine

Hershey, Pennsylvania

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Michiel F. Dirkx, MD, PhD
 

Neurologist

Radboud University Medical Center

 Nijmegen, Netherlands

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Steven Frucht, MD
 

Professor, Department of Neurology Director, Division of Parkinson's and Movement Disorders

NYU Grossman School of Medicine

New York, New York

Hirofumi Fujita, MD, PhD
 

Assistant Professor

Cain Scholar in Mobility Disorders

UT Southwestern Medical Center
Dallas, Texas

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Robert A. Hauser MD, MBA
 

Professor of Neurology

Director
USF Parkinson’s Disease and Movement Disorders Center
Tampa, Florida

Rick Helmich, MD, PhD
 

Consultant Neurologist

Radboud University Nijmegen Medical Center

Nijmegen, Netherlands

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Kandice Kapinos, PhD
 

Adjunct Associate Professor

UT Southwestern Medical Center
Dallas, Texas

Ami Kumar PhD
 

Postdoctoral Research Fellow

Columbia University Irving Medical Center
New York, New York

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Phyllis L. Faust, MD, PhD
 

Professor, Department of Pathology and Cell Biology

Columbia University Vagelos College of Physicians and Surgeons

New York, New York

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Lauren H Hammer, MD, PhD
 

Assistant Professor of Neurology Hammer Neuromodulation Laboratory

University of Pennsylvania

Philadelphia, Pennsylvania

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Hyder Jinnah, MD, PhD
 

Departments of Neurology and Human Genetics

Emory University School of Medicine
Atlanta, Georgia

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Sheng-Han Kuo, MD
 

Associate Professor of Neurology

Columbia University Irving Medical Center
New York, New York

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Max Laansma, PhD

​

PhD Candidate

Amsterdam UMC

​Amsterdam, Netherlands 

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Katherine Longardner, MD

​

Assistant Professor of Neurosciences

University of California San Diego

La Jolla, Califonia

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Abhishek Lenka, MD, PhD
 

Assistant Professor

Department of Neurology 

VCU Parkinson's & Movement Disorders Center 

VCU Comprehensive Autonomic Center

Virginia Commonwealth University School of Medicine
Richmond, Virginia

Peter A. LeWitt, MD
 

Departments of Neurology

Henry Ford Hospital and Wayne State University School of Medicine

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Antonella Macerollo, MD PhD, FRCP FEBN F

Elan D. Louis, MD, MS
 

Professor of Neurology

Linda and Mitch Hart Distinguished Chair in Neurology

University of Texas Southwestern Medical Center
Dallas, Texas

Antonella Macerollo, MD PhD, FRCP FEBN FEAN

​

Consultant Neurologist (Movement Disorders, DBS, MRIgFUS)

​

Clinical Associate Professor (Honorary), University of Liverpool

Liverpool, United Kingdom

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Muthuraman Muthuraman, PhD
 

Associate Professor

Chair of the Informatics for Medical Technology

University Augsburg

​Augsburg, Germany

Giovanni Oliveros
 

Postdoctoral Research Scientist in the Department of Pathology and Cell Biology, Dept of Pathology

Columbia University Irving Medical Center
New York, New York

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Rajesh Pahwa, MD
 

Professor, Neurology; Director Parkinson's Disease and Movement Disorder Center

The University of Kansas Medial Center
Kansas City, Kansas

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Ming-Kai Pan, MD, PhD
 

Assistant Professor of Pharmacology Institute and Molecular Imaging Center

National Taiwan University
Taipei, Taiwan

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William Ondo, MD
 

Director-Movement Disorders Clinic

Houston Methodist Neurological Institute
Houston, Texas

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Sanjay, Pandey MBBS, MD, DNB, DM, FIAN
 

Professor and Head

Department of Neurology and Stroke Medicine

Amrita Institute of Medical Sciences
Kerala, India

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Jacopo Pasquini, MD
 

Post Doctoral Researcher

University of Pisa
Pisa PI, Italy

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Daniel Roque, MD

​

Professor of Neurology

Vice Chair of Ambulatory Affairs

Director of the UNC Movement Disorders Neuromodulation Program

Adjunct Associate Professor, UNC Neurosurgery

UNC Hospitals Neurology Clinic

Chapel Hill, NC

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Aasef Shaikh, MD, PhD
 

Penni and Stephen Weinberg Chair in Brain Health

Vice Chair for Research, Department of Neurology

University Hospitals
Cleveland, OH

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Ludy Shih, MD, MMSc, FAAN, FANA
 

Department of Neurology

Beth Israel Deaconess Medical Center

Harvard Medical School
Boston, Massachusetts 

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Holly Shill, MD, FAAN
 

Director

 Lonnie and Muhammad Ali Movement Disorder Center, Barrow Neurological Institute

​

Bob and Renee Parsons Chair in Parkinson’s Disease and Movement Disorders
Phoenix, Arizona

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Kristina Simonyan, MD, PhD
 

John W. Merriam and William W. Montgomery Professor and Vice Chair for Clinical Research

​

Investigator in Neurology

Massachusetts General Hospital

Boston, Massachusetts

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​Nienke-Timmermans PhD

 

PhD candidate

Radboud University Medical Center

Nijmegen, Netherlands

Aparna Wagle Shukla, MD
 

Professor of Neurology Director, Clinical Trials

University of Florida Health
Gainesville, Florida 

Theresa Zesiewicz, MD, FAAN
 

Professor

Department of Neurology

University of South Florida
Tampa, Florida

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​Endorsed by the International Parkinson and Movement Disorder Society

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