TREMOR CONGRESS
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SCHEDULE
Day 1 April 30th
7:30 AM Registration and Continental Breakfast
8:25 AM Welcome (5 min)
Sheng-Han Kuo & Aparna Wagle Shukla
Session 1: Recent Advances in Tremor Physiology and Clinical Science
Moderator: Shabbir Merchant
8:30 AM The Global Burden of Essential Tremor and the Economic Costs of Treatment
Kandice Kapinos
8:50 AM Prevalence and Clinical Significance of Common and Rare Tremor Disorders
Sanjay Pandey
9:10 AM Postmortem-based Diagnostic Criteria for Essential Tremor
Phyllis Faust
9:30 AM Neuropathological Basis of ET-Dementia
Elan Louis
9:50 AM Work and Activity Impairment in Individuals with Essential Tremor
Ludy Shih
10:10 AM Distinguishing Parkinson’s Disease Tremor from Essential Tremor: Clinical and Experimental
Tools
Matteo Bologna
10:30 AM Cerebellar EEG Signatures of Essential Tremor
Ami Kumar
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10:40 AM High Spatiotemporal ECoG Recordings in an Essential Tremor Patient Reveal Frequency- Specific Spatial Power Distributions in the Primary Motor Cortex
Aaron H Berson
10:50 AM Break (20 min)
Session 2: Basic and Translational Research of Tremors: What Do We Learn?
Moderator: Ilaria Balbo
11:10 AM Frequency Encoding Mechanism of Essential Tremor
Ming-Kai Pan
11:30 AM Thalamic Gating of Movement Frequency: Implications in Tremor Disorders
Christopher Chen
11:50 AM Neurophysiologic Signatures of Essential Tremor and Implications for DBS
Lauren Hammer
12:10 PM Bi-directional Regulation of Cerebellar Physiology of Ataxia and Tremor
Sheng-Han Kuo
12:30 PM Purkinje Cell Axonal Pathology of Essential Tremor
Hirofumi Fujita
12:50 PM Proteomic Analysis of the Cerebellar – Olivary Tremor Circuit Reveals Myelination and Cholinergic Signaling Defects in Essential Tremor
Giovanni Oliveros
Lunch 1:00 PM to 2:00 PM
Session 3: From Mechanisms to Medicine: Identifying the Key Pathophysiological Basis Underlying Essential Tremor and Parkinson’s Disease for Targeted Therapies
Moderator: Peter A. LeWitt
2:00 PM Initial Poll
Peter A. LeWitt
2:05 PM Hyper-excitability of the T-type Calcium Channels is the Key Mechanism for Essential Tremor
Theresa Zesiewicz
2:20 PM Insufficient GABA Mechanism is the Key Mechanism for Essential Tremor
William Ondo
2:35 PM Dopaminergic Dysfunction: A Central Contributor to Parkinsonian Tremor
Michiel F. Dirkx
2:50 PM Serotonin and not Dopamine: A Central Contributor to Parkinsonian Tremor
Jacopo Pasquini
3:05 PM Discussion
Peter A. LeWitt
3:30 PM Refreshment Break (30 min)
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4:00 PM Cala Health Sponsored Talk
Session 4: Industry Perspective
Moderator: Daniel Roque
4:30 PM Industry Partner Presentations
5:30 PM Panel Discussion - Academic and Industry Collaboration
Moderators: Sheng-Han Kuo & Shabbir Merchant
6:00 PM Adjourn
6:30 PM Reception and Dinner: Sunset Cruise at Tampa Bay
Day 2 May 1st
7:00 AM Registration; Continental Breakfast
Session 5: Recent Advances in Imaging of Tremor Disorders
Moderator: Luca Marsili
8:00 AM New Insights of Dystonic Voice Tremor Imaging
Kristina Simonyan
8:20 AM Enigma Tremor
Arthur Buijink
8:40 AM Updates on Parkinson’s Disease Tremor Imaging
Rick Helmich
9:00 AM Deciphering How Noninvasive TAPS Treats Refractory Essential Tremor: Electrophysiologic Evidence of VIM Modulation and Longitudinal PET-Based Network Effects
Cuong P. Luu
9:10 AM The Cerebral Mechanisms of Re-emergent Tremor in Parkinson’s Disease
Kevin Van Den Berg ​
9:20 AM Refreshment Break (20 min)
Session 6: Advances in Therapeutic Development for Tremor
Moderator: Jerry D. Fenn
9:40 AM Peripheral Neuromodulation: Current Strategies and Future Directions in Tremor Management
Rajesh Pahwa
10:00 AM New Horizons in Tremor Management: Pharmacological Innovations and Clinical Trials
Peter A. LeWitt
10:20 AM Advances in DBS Therapy for Tremor: Evolvoing Target, Adaptive Systems, and
Precision Neuromodulation
Aparna Wagle Shukla
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10:40 AM Thermal Lesioning with Precision: Updates on Focused Ultrasound Therapy for Tremor
Antonella Macerollo
11:00 AM Machine Learning Approaches for Understanding and Managing Tremor Disorders
Muthuraman Muthuraman
11:20 AM Artificial Intelligence in Tremor Diagnosis and Management: Current Applications and
Future Directions
Nienke A Timmermans
11:40 AM Thalamic High-Frequency Oscillations During Speech Production in Essential Tremor with and without Voice Tremor
Giovanni Battistella
11:50 AM Movement Neurophysiology Studies for Tremor: Clinical Practice Patterns and Standardization
Marcus Callister
12:00 PM Poster Session (90 min)
-1:30 PM
12:30 PM Lunch and Learn
Session 7: Advances in Analysis of Tremor
Moderator: Jun Yu
1:30 PM Electrophysiological Tools for Tremor Evaluation: What Every Clinician Should Know
Katie Longardner & Marcus Callister
1:50 PM Decoding Head Tremor: Electrophysiological Tools for Differential Diagnosis and Management
Aasef Shaikh
2:10 PM Smart Wearables for Tremor Detection: Algorithms, Accuracy, and Clinical Relevance
Steve Charles
Session 8: Clinical and Research Mentoring (60 min)
Moderator: Katie Longardner
2:30 PM What Do We Need to Move Tremor Research Forward? Perspectives for the Next Generation
Robert A. Hauser, Holly Shill, Abhishek Lenka, Daniel Roque
3:30 PM Refreshment Break (20 min)
Session 9: Challenging Cases & Video Rounds
Moderator: Aparna Wagle Shukla
3:50 PM Tremor Video Rounds: Case-Based Learning and Diagnostic Pearls
Steve Frucht & Hyder Jinnah
4:50 PM Closing Remarks
Sheng-Han Kuo & Aparna Wagle Shukla
SPEAKERS
Matteo Bologna MD, PhD
Associate Professor of Neurology
University of Rome La Sapienza
Rome, Italy
Steven Charles, MD, PhD
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Neuroscience Center Director, Associate Professor, Mechanical Engineering
Brigham Young University
Provo, Utah
Arthur Buijink, MD PhD
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Neurologist
Amsterdam University Medical Center
Amsterdam, the Netherlands
Christopher Chen, PhD
Assistant Professor, Neuroscience and Experimental Therapeutics
Penn State College of Medicine
Hershey, Pennsylvania
Marcus Callister, MD
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Clinician Investigator, Instructor
NSI Neuro Behavioral MGPO, Mass General Research Institute
Massachusetts General Hospital
Boston, Massachusetts
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Michiel F. Dirkx, MD, PhD
Neurologist
Radboud University Medical Center
Nijmegen, Netherlands
Phyllis L. Faust, MD, PhD
Professor, Department of Pathology and Cell Biology
Columbia University Vagelos College of Physicians and Surgeons
New York, New York
Steven Frucht, MD
Professor, Department of Neurology Director, Division of Parkinson's and Movement Disorders
NYU Grossman School of Medicine
New York, New York
Hirofumi Fujita, MD, PhD
Assistant Professor
Cain Scholar in Mobility Disorders
UT Southwestern Medical Center
Dallas, Texas
Lauren H Hammer, MD, PhD
Assistant Professor of Neurology Hammer Neuromodulation Laboratory
University of Pennsylvania
Philadelphia, Pennsylvania
Hyder Jinnah, MD, PhD
Departments of Neurology and Human Genetics
Emory University School of Medicine
Atlanta, Georgia
Robert A. Hauser MD, MBA
Professor of Neurology
Director
USF Parkinson’s Disease and Movement Disorders Center
Tampa, Florida
Rick Helmich, MD, PhD
Consultant Neurologist
Radboud University Nijmegen Medical Center
Nijmegen, Netherlands
Kandice Kapinos, PhD
Adjunct Associate Professor
UT Southwestern Medical Center
Dallas, Texas
Ami Kumar PhD
Postdoctoral Research Fellow
Columbia University Irving Medical Center
New York, New York
Sheng-Han Kuo, MD
Associate Professor of Neurology
Columbia University Irving Medical Center
New York, New York
Abhishek Lenka, MD, PhD
Assistant Professor
Department of Neurology
VCU Parkinson's & Movement Disorders Center
VCU Comprehensive Autonomic Center
Virginia Commonwealth University School of Medicine
Richmond, Virginia
Peter A. LeWitt, MD
Departments of Neurology
Henry Ford Hospital and Wayne State University School of Medicine
Katherine Longardner, MD
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Assistant Professor of Neurosciences
University of California San Diego
La Jolla, Califonia
Elan D. Louis, MD, MS
Professor of Neurology
Linda and Mitch Hart Distinguished Chair in Neurology
University of Texas Southwestern Medical Center
Dallas, Texas
Antonella Macerollo, MD PhD, FRCP FEBN FEAN
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Consultant Neurologist (Movement Disorders, DBS, MRIgFUS)
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Clinical Associate Professor (Honorary), University of Liverpool
Liverpool, United Kingdom
Muthuraman Muthuraman, PhD
Associate Professor
Chair of the Informatics for Medical Technology
University Augsburg
​Augsburg, Germany
Giovanni Oliveros
Postdoctoral Research Scientist in the Department of Pathology and Cell Biology, Dept of Pathology
Columbia University Irving Medical Center
New York, New York
William Ondo, MD
Director-Movement Disorders Clinic
Houston Methodist Neurological Institute
Houston, Texas
Rajesh Pahwa, MD
Professor, Neurology; Director Parkinson's Disease and Movement Disorder Center
The University of Kansas Medial Center
Kansas City, Kansas
Ming-Kai Pan, MD, PhD
Assistant Professor of Pharmacology Institute and Molecular Imaging Center
National Taiwan University
Taipei, Taiwan
Sanjay, Pandey MBBS, MD, DNB, DM, FIAN
Professor and Head
Department of Neurology and Stroke Medicine
Amrita Institute of Medical Sciences
Kerala, India
Jacopo Pasquini, MD
Post Doctoral Researcher
University of Pisa
Pisa PI, Italy
Daniel Roque, MD
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Professor of Neurology
Vice Chair of Ambulatory Affairs
Director of the UNC Movement Disorders Neuromodulation Program
Adjunct Associate Professor, UNC Neurosurgery
UNC Hospitals Neurology Clinic
Chapel Hill, NC
Aasef Shaikh, MD, PhD
Penni and Stephen Weinberg Chair in Brain Health
Vice Chair for Research, Department of Neurology
University Hospitals
Cleveland, OH
Ludy Shih, MD, MMSc, FAAN, FANA
Department of Neurology
Beth Israel Deaconess Medical Center
Harvard Medical School
Boston, Massachusetts
​Nienke-Timmermans PhD
PhD candidate
Radboud University Medical Center
Nijmegen, Netherlands
Holly Shill, MD, FAAN
Director
Lonnie and Muhammad Ali Movement Disorder Center, Barrow Neurological Institute
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Bob and Renee Parsons Chair in Parkinson’s Disease and Movement Disorders
Phoenix, Arizona
Kristina Simonyan, MD, PhD
John W. Merriam and William W. Montgomery Professor and Vice Chair for Clinical Research
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Investigator in Neurology
Massachusetts General Hospital
Boston, Massachusetts
Aparna Wagle Shukla, MD
Professor of Neurology Director, Clinical Trials
University of Florida Health
Gainesville, Florida
Theresa Zesiewicz, MD, FAAN
Professor
Department of Neurology
University of South Florida
Tampa, Florida
